The first report on kanna comes from Peter Floris, who mentions the plant in his journey to the East Indies in the globe 1611-1615. In Floris` report, kanna appears to be similar to Korean ginseng in that it has « an outstanding reputation in China as a tonic. » However, he was unable to procure fresh equipment. Jan van Riebeeck wrote the first known written report on the use of the complex in 1662. Van Riebeeck traded indigenous tribes in southern Africa and exchanged sheep for kanna, which was again identified as a ginseng-like herb. In South Africa, a kanna extract is sold under the name Zembrin, which is only available by prescription. Kanna can also be added to beer to provide a psychoactive effect or induce fermentation. Chewing kanna after smoking cannabis can enhance its effects. Kanna is said to suppress both the effects of tobacco (Nicotiana tabacum) and the craving for nicotine. Since kanna is a serotonin reuptake inhibitor, it should also not be used with other SSRIs (serotonin reuptake inhibitors). Too much serotonin in the nervous system can cause a condition called serotonin syndrome. In smaller cases, people with serotonin syndrome report symptoms such as tremors, muscle twitching, anxiety, insomnia, and increased heart rate. When serotonin levels become high enough, serotonin syndrome can cause seizures, delirium, and extremely high body temperature.
In extreme cases, a person suffering from serotonin syndrome can fall into a coma. The symptoms of serotonin syndrome vary from person to person, ranging from mild to life-threatening. Although kanna is legal in all countries, it has received little attention outside of South Africa. Its main active ingredients are mesembrin and meembrénon. Although some authors have described it as a hallucinogen, kanna is only mildly psychoactive and is often used with other plants, including cannabis or dagga (lion`s tail or Leonotis leonurus), but it is not considered psychedelic. Synthetic cathinones were first detected in 2008 by our web mapping research group (4). They are structurally similar to amphetamines/catecholamines, with subtle variations that alter their chemical properties, potency, pharmacokinetics and pharmacodynamics. Their popularity has been driven by the lack of availability or low purity of cocaine or 3,4-methylenedioxy-methamphetamine (MDMA) combined with few or no legal restrictions (3). Other methods include making a tea from the dried herb, sniffing very finely ground powder, alone or with tobacco, or smoking kanna powder alone or in combination with Cannabis sativa or lion`s tail. Often, plant material may be too coarse to sniff, so it is best to spray the prepared grass in a multipurpose spice grinder, and then sniff the very fine powder that accumulates inside the lid.
As little as 20-30 mg may be needed to sniff. Sceletium species have an exceptionally long history of use, with the first documented reports of their use by Van Riebeeck (c. 1660) as a subject of trade of the Khoi. It was probably used by hunter-gatherers and shepherds in prehistoric times. An early illustration of a sceletium plant can be found in the journal of Governor van der Stel`s expedition to Namaqualand in 1685, who noted that the product had considerable potential as a commercial product due to its « pleasant and tasty taste ». There are two surviving copies of the painting, both showing a typical Sceletium flower and the characteristic skeletonized leaves reflected in the genus name Sceletium, accompanied by the following information, translated from the original Dutch: « This plant is found among the Namaquas and only on some of their mountains. It is collected in October and is called Canna. It is held in such high esteem by them and the surrounding tribes that betel or areca is held in such high esteem by the Indians.
In 1738, Kolben called Kanna (or Channa) « the greatest listener of spirits and the noblest restorer in the world » . In 1924, Kolben referred to a plant used for the pleasure of the Khoi, which they « chewed, held in their mouths for a while, and became so excited… . Traditional use as chewing is also described by Commelin 1692 , Thunberg ca. 1770  and many other sources [1, 6, 12, 14-23]. People experiment with microdosing various psychoactive compounds. If you`re curious about how to microdose with Kanna and want to learn how to get started with microdosing with a scientific, step-by-step process, Third Wave`s new and improved microdosing course can show you how. The course walks you through the basics, then digs much deeper and helps you adapt your routine to your personal goals. The course doesn`t explicitly teach you how to use kanna, but it can help you develop a strategy for incorporating it into your life for optimal benefits. This regulatory landscape creates a mystery for some ingredients, such as sceletium. In the category of foods (and dietary supplements) it would be considered « novel », although it is regulated as a food in its country of origin, it is unlikely that the competent authorities will consider it appropriate due to its predominant history as a traditional herbal medicine.
Since it has not been on the EU market for at least 15 years and is unlikely to be considered suitable for over-the-counter products, it is not considered THMP. It has no taste, fragrance or cosmetic uses. This leaves only one category for legal market access by MA. Drug development, in turn, requires significant investments and carries significant risks for such investments. The amount of research already done and available to the public gives little appetite for market forces capable of curbing such investments, as there is virtually no way to protect product development from competition and ensure profitability. Thus, the ingredient becomes a « hot potato », although interesting, unique and potentially beneficial in a therapeutic setting, no one can or wants to « touch » appreciably. And indeed, there are still no legal products containing sceletium on the European market. We searched Medline/PubMed for studies using the terms `new psychoactive substances`, `new psychoactive substances`, `legal highs`, `synthetic drugs`, `research chemicals`, `smart drugs` and `emerging drugs`. Similar research was conducted for major substance groups and associated psychiatric manifestations. While no information on index substances was available in the peer-reviewed literature, some websites were identified by entering the keywords of the index substances into Google, selecting and analyzing forums/threads. That`s all well and good, haha. But still! What typical member of society would cultivate their own salvia for divination? These sheep-kissing people probably don`t even know how to spell the prophecy.
not to mention its meaning. I just think that if Sal were legal to buy, as is the case in New Zealand, then a lot of idiots would abuse the extract to sell it. I just can`t imagine many people going so far as to cultivate their own business when it means putting in time, patience, and effort to get the same effect they would get from something they could just buy.